AN IN SILICO HIGH-THROUGHPUT SCREEN IDENTIFIES POTENTIAL SELECTIVE INHIBITORS FOR THE NON-RECEPTOR TYROSINE KINASE PYK2

An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2

Tomer Meirson, Abraham O Samson, Hava Gil-Henn Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel Abstract: The non-receptor tyrosine kinase proline-rich tyrosine kinase 2 (Pyk2) is a critical mediator of signaling from cell surface growth factor and adhesion receptors to cell migration, proliferation, and survival.Emerging evid

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Online Convolutional Neural Network-based anomaly detection and quality control for Fused Filament Fabrication process

Additive Manufacturing (AM) technologies are experiencing rapid growth in the past decades.Critical objectives for the AM processes are how to ensure product quality and process consistency.The detection and correction of part and process anomalies show great promises and challenges.This paper presents an online laser-based process monitoring and c

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Esthesioneuroblastoma in a boy with 47, XYY karyotype

Neuroblastomas are sometimes associated with abnormal constitutional karyotypes, but the XYY karyotype has been rarely described in neuroblastomas.Here, we report a case of an esthesioneuroblastoma in a boy with a 47, XYY karyotype.A 6-year-old chicago cubs tumbler boy was admitted to our hospital because of nasal obstruction and palpable cervical

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